Good At

The treatment focuses primarily on patients with advanced peritoneal metastasis from tumors. It also includes cases of borderline primary peritoneal tumors. Through multidisciplinary collaboration among surgeons, gastroenterologists, oncologists, and radiologists, more aggressive and effective treatment methods are employed. This approach aims to control the spread of tumors within the abdominal cavity, slow down the progression of malignant ascites, and improve the quality of life for patients.

Introduction

Digestive tract tumors, such as gastric cancer and colorectal cancer, can lead to peritoneal metastasis in advanced stages. As a result, there is often a significant amount of fluid accumulation in the abdominal cavity, causing severe bloating, difficulty eating, and extreme weight loss. These symptoms are among the main causes of death from digestive tract tumors. In the past, the primary treatment methods involved systemic chemotherapy, including the use of diuretics to control fluid accumulation or repeated paracentesis to drain the fluid. However, these methods were often difficult for patients to tolerate, and their effectiveness in controlling fluid accumulation was limited. In recent years, progress has been made in treating peritoneal metastases caused by malignant tumors. This includes several approaches: 1) Laparoscopic exploration, which not only helps in early diagnosis and allows for genetic testing, but also enables precise PCI scoring; 2) Combination of intra-abdominal chemotherapy with systemic therapy has shown promising results in controlling fluid accumulation and alleviating symptoms, and has become a recommended option according to guidelines and consensus statements; 3) Advances in immunotherapy and targeted therapy have also improved patient outcomes to some extent; 4) Surgical resection of limited peritoneal metastases and complete tumor removal have also shown encouraging prospects. Currently, there are few specialized outpatient clinics for peritoneal metastases and malignant ascites. Patients often lack access to professional and targeted treatment.